Total joint replacement has become a widely accepted treatment for many destructive joint diseases.
Failure of the two most commonly and most successfully replaced joints, the knee and the hip, occur due to infection, or to wear of the joint’s weight bearing surfaces which generates debris. In response to this debris, a biological reaction occurs that eventually leads to implant failure.
The required surgical revision can be severely complicated by progressing tissue damage: bone loss, pseudotumors, adverse local tissue reaction, necrosis, muscle mass loss, to name a few. Stage I and II Osteoarthritis and implant failure are not well detected by radiography and conventional MRI techniques1.
1. Oei EH1, et. al. Quantitative radiological imaging techniques for articular cartilage composition: Towards early diagnosis and development of disease-modifying therapeutics for osteoarthritis., Arthritis Care Res (Hoboken). 2014 Feb 27. doi: 10.1002/acr.22316
OrthoSonos patents issued as of October 2016
EU 003419035-0001 to 0008
EU 003477082-0001 & 0002
EU 003465871-0001 & 0002
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