OrthoSonos™

Photo: Orthosonos

Clinical Challenge:

  • Total joint replacement has become a widely accepted treatment for many destructive joint diseases.
  • Failure of the two most commonly and most successfully replaced joints, the knee and the hip, occur due to infection, or to wear of the joint's weight bearing surfaces which generates debris. In response to this debris, a biological reaction occurs that eventually leads to implant failure.
  • The required surgical revision can be severely complicated by progressing tissue damage (bone loss, pseudotumors, adverse local tissue reaction, necrosis, muscle mass loss, to name a few).
  • Stage I and II Osteoarthritis and implant failure are not well detected by radiography and conventional MRI techniques.

Large Market:

  • In the US, the demand for primary total hip arthroplasties (THA) and total knee arthroplasties (TKA) is estimated to grow to 600,000 and 3.5 million procedures a year respectively, by 2030.
  • If the historical growth trajectory of joint replacement surgeries continues, demand for primary THA and TKA among patients less than 65 years old is projected to exceed 50% of THA and TKA patients of all ages.

BBI Solution:

BBI is developing the OrthoSonos, an Acoustic Emission (AE) based joint health monitor for natural and artificial joints.

OrthoSonos Features:

  • Assessment performed through full dynamic range of joint motion, rather than current, static view
  • Easy to use by all clinicians
  • Non-invasive
  • Cost effective
  • Continuous or single use monitoring
  • Single reported metric of joint friction: the OrthoSonos Health Index

OrthoSonos™ is not available for sale. For additional information on orthopedic health, review the following articles:

Kurtz S, Ong K, Lau E, Mowat F, Halpern M. Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. J Bone Joint Surg Am. 2007;89(4):780-785.

Kurtz S, Lau E, Ong K, Zhao K, Kelly M, Bozic K. Future Young Patient Demand for Primary and Revision Joint Replacement: National Projections from 2010 to 2030. Clinical Orthopaedics and Related Research. 2009;467(10):2606-2612.

Oei EH1, et. al. Quantitative radiological imaging techniques for articular cartilage composition: Towards early diagnosis and development of disease-modifying therapeutics for osteoarthritis., Arthritis Care Res (Hoboken). 2014 Feb 27. doi: 10.1002/acr.22316

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